Developing an Irreversible Inhibitor of Human DDAH-1, an Enzyme Upregulated in Melanoma
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چکیده
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development and implementation of an optimized control strategy for induction machine in an electric vehicle
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7or-(4'-Amino)phenylthio-l,4-androstadiene-3,17-dione(7a-APTADD), a potent enzyme-activated irreversible inhibitor, was examined in two different human cell culture lines, MCF-7 human mammary carcinoma cells and JAr choriocarcinoma cells. Both the MCF-7 and JAr cell culture systems exhibit aromatase activity, and 7a-APTADD was evaluated for its aromatase-inhibitory activity, for its ability to ...
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ژورنال
عنوان ژورنال: ChemMedChem
سال: 2014
ISSN: 1860-7179
DOI: 10.1002/cmdc.201300557